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Acetoacetic acid sodium salt

CAS No. 623-58-5

Acetoacetic acid sodium salt( —— )

Catalog No. M24625 CAS No. 623-58-5

Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 53 In Stock
5MG 87 In Stock
10MG 132 In Stock
25MG 216 In Stock
50MG 324 In Stock
100MG 482 In Stock
500MG 1044 In Stock
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Biological Information

  • Product Name
    Acetoacetic acid sodium salt
  • Note
    Research use only, not for human use.
  • Brief Description
    Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes.
  • Description
    Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes.
  • In Vitro
    Acetoacetic acid sodium induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes.Acetoacetic acid (0.6, 2.4, 4.8 mM) increases malondialdehyde (MDA) content in high-dose group (GH) group, decreases mRNA expression of Mn SOD, Cu/Zn SOD, and glutathione peroxidase (GSH-Px) in all groups, lowers catalase (CAT) mRNA expression in medial-dose group (GM), and GH groups. In addition, Acetoacetic acid down-regulates the mRNA expression of apolipoprotein B100 (ApoB100), apolipoprotein E (ApoE), and low density lipoprotein receptor (LDLR). Thus, VLDL assembly is decreased andtriglyceride (TG) accumulation is increased in these bovine hepatocytes.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    623-58-5
  • Formula Weight
    124.07
  • Molecular Formula
    C4H5NaO3
  • Purity
    >98% (HPLC)
  • Solubility
    H2O:50 mg/mL (403.00 mM; Need ultrasonic)
  • SMILES
    CC(=O)CC(=O)[O-].[Na+]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Shi X, et al. Acetoacetic acid induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes. J Dairy Res. 2016 Nov;83(4):442-446.
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